Safety and efficacy of methotrexate (0.3 mg/kg/week) versus a combination of methotrexate (0.15 mg/kg/week) with cyclosporine (2.5 mg/kg/day) in chronic plaque psoriasis: A randomised non-blinded controlled trial
نویسندگان
چکیده
منابع مشابه
Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis.
BACKGROUND Methotrexate and cyclosporine are well-known systemic therapies for moderate-to-severe chronic plaque psoriasis. We conducted a randomized, controlled trial comparing methotrexate and cyclosporine in terms of effectiveness, side effects, and the quality of life. METHODS A total of 88 patients with moderate-to-severe psoriasis were randomly assigned to treatment for 16 weeks with ei...
متن کاملEfficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial
OBJECTIVE CONCERTO was a randomised, double-blind, parallel-armed study of methotrexate (MTX) in combination with adalimumab to assess whether an increasing trend of efficacy and decreased safety exists when increasing MTX dose in patients with early rheumatoid arthritis (RA). METHODS Early, biologic and MTX-naive RA patients (N=395) were evenly randomised to open-label adalimumab (40 mg ever...
متن کاملEfficacy of Methotrexate in patients with plaque type psoriasis
OBJECTIVE To assess the efficacy of Methotrexate in patients with plaque type psoriasis. METHODS This descriptive study was conducted in the department of Dermatology, Civil Hospital Karachi from September 2009 to March 2010. Seventy three patients between 18 to 50 years of age suffering from plaque type psoriasis with PASI score of >10 were included in the study after taking the informed con...
متن کاملa comparison of teachers and supervisors, with respect to teacher efficacy and reflection
supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...
15 صفحه اولEfficacy of combination therapy of Methotrexate and Vitamin A in low risk gestational trophoblastic neoplasia treatment
Introduction: Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the e...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology
سال: 2021
ISSN: 0378-6323
DOI: 10.25259/ijdvl_613_19